Active Vitamin D Receptor (VDR)
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Catalog number
APA475Hu01-5MG
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Price
Please ask
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Size
5MG
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Description
Recombinant Human Vitamin D Receptor expressed in: E.coli
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Specifications
Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Met272~Ser427; Purity: > 90%; Endotoxin level:
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Additional_information
Uniprot ID: P11473; Buffer composition: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 21.6kDa; Isoelectric Point: 6.5
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Storage_and_shipping
Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
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Notes
Research Use Only.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
VDR
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Short name
Active Vitamin D Receptor (VDR)
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Alternative name
functionnal Vitamin D Receptor (vitamin D (1,25- dihydroxyvitamin D3) receptor)
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Alternative to gene target
vitamin D (1,25- dihydroxyvitamin D3) receptor, NR1I1 and PPP1R163, VDR and IDBG-29237 and ENSG00000111424 and 7421, lithocholic acid binding, nuclei, Vdr and IDBG-179227 and ENSMUSG00000022479 and 22337, VDR and IDBG-633008 and ENSBTAG00000016414 and 533656
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Gene info
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Identity
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Gene
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Long gene name
vitamin D receptor
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Synonyms gene name
- vitamin D (1,25- dihydroxyvitamin D3) receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1989-06-30
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Entrez gene record
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Pubmed identfication
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Classification
- Protein phosphatase 1 regulatory subunits
- Nuclear receptor subfamily 1 group I
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VEGA ID
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Locus Specific Databases
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