Vitamin D3 Receptor

Products_type

Antibody
Products_short_name

[Vitamin D3 Receptor]
Other_names

[vitamin D3 receptor isoform VDRAx; Vitamin D3 receptor; vitamin D3 receptor; vitamin D receptor; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1]
Other_gene_names

[VDR; VDR; NR1I1; PPP1R163; NR1I1; VDR]
Clone

[1G2]
Reactivity

Mammals, Birds. Other vertebrates not tested.
Form

Diluted ascites containing 0.01% sodium azide
Storage_stability

Store at -20 degree C.
Tested_application

Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB), Functional Inhibition (azide-free solution required)
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Identity

HGNC:12679
Gene

VDR
Long gene name

vitamin D receptor
Synonyms gene name
- vitamin D (1,25- dihydroxyvitamin D3) receptor
Synonyms
- NR1I1
- PPP1R163
Synonyms name
- protein phosphatase 1, regulatory subunit 163
- 1,25- dihydroxyvitamin D3 receptor
GenBank acession
- J03258
Locus

12q13.11
Discovery year

1989-06-30
Entrez gene record

7421
Pubmed identfication
- 1662663
Classification
- Protein phosphatase 1 regulatory subunits
- Nuclear receptor subfamily 1 group I
VEGA ID

OTTHUMG00000169890
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database