PC4 Antibody

• Catalog number
  PB10098
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  PC4
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human PC4 (96-127aa MKPGRKGISLNPEQWSQLKEQISDIDDAVRKL), different from the related mouse and rat sequences by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the PC4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The PC4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Activated RNA polymerase II transcriptional coactivator p15, also known as positive cofactor 4 (PC4) or SUB1 homolog, is a protein that in humans is encoded by the SUB1 gene. This gene is mapped to 5p13.3. The transcriptional cofactor PC4 is an ancient single-strand DNA (ssDNA)-binding protein that has a homologue in bacteriophage T5 where it is likely the elusive replicative ssDNA-binding protein. The recombinant PC4 is shown to function identically to the native protein through its interaction with TAFs.
• Related articles
  1. "Entrez Gene SUB1: SUB1 homolog (S. cerevisiae)". 2. Kretzschmar M, Kaiser K, Lottspeich F, Meisterernst M (August 1994). "A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators". Cell 78 (3): 525–34. 3. Ge H, Roeder RG (August 1994). "Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes". Cell 78 (3): 513–23.
• Gene Name
  SUB1
• Protein Name
  Activated RNA polymerase II transcriptional coactivator p15
• Gene Full Name
  SUB1 homolog, transcriptional regulator
• Synonyms
  p14 | P15 | PC4 | PC4 LSB | Positive cofactor 4 | RPO2TC1 | Sub1 | P53999
• Uniprot ID
  P53999
• Entrez GeneID
  10923
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PC4  
• Gene symbol
  IFRD1, SUB1, PCSK4
• Short name
  PC4 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  PC4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5456
• Gene
  IFRD1
• Long gene name
  interferon related developmental regulator 1
• Synonyms gene name
  • interferon-related developmental regulator 1
• Synonyms
  • PC4
  • TIS7
• GenBank acession
  • Y10313
• Locus
  7q31.1
• Discovery year
  1998-01-21
• Entrez gene record
  3475
• Pubmed identfication
  • 9722946
• RefSeq identity
  • NM_001550
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000155124

Gene info

• Identity
  HGNC:19985
• Gene
  SUB1
• Long gene name
  SUB1 regulator of transcription
• Synonyms gene name
  • SUB1 homolog (S. cerevisiae)
  • SUB1 homolog, transcriptional regulator
• Synonyms
  • PC4
  • p15
  • p14
• Synonyms name
  • positive cofactor 4
• GenBank acession
  • X79805
• Locus
  5p13.3
• Discovery year
  2005-08-19
• Entrez gene record
  10923
• Pubmed identfication
  • 8062392
  • 8062391
  • 28369605
• RefSeq identity
  • NM_006713
• VEGA ID
  OTTHUMG00000131071

Gene info

• Identity
  HGNC:8746
• Gene
  PCSK4
• Long gene name
  proprotein convertase subtilisin/kexin type 4
• Synonyms
  • PC4
  • SPC5
  • DKFZp434B217
  • MGC34749
• GenBank acession
  • AK057235
• Locus
  19p13.3
• Discovery year
  1993-10-19
• Entrez gene record
  54760
• Pubmed identfication
  • 7782070
• RefSeq identity
  • NM_017573
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000128541

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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