MEF2A Antibody

• Catalog number
  PB9953
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  MEF2A
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human MEF2A (466-507aa DGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAW VT), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the MEF2A Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The MEF2A Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. It is mapped to 15q26. The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
• Related articles
  1. Bhagavatula, M. R. K., Fan, C., Shen, G.-Q., Cassano, J., Plow, E. F., Topol, E. J., Wang, Q. Transcription factor MEF2A mutations in patients with coronary artery disease. Hum. Molec. Genet. 13: 3181-3188, 2004. 2. Flavell, S. W., Cowan, C. W., Kim, T.-K., Greer, P. L., Lin, Y., Paradis, S., Griffith, E. C., Hu, L. S., Chen, C., Greenberg, M. E. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311: 1008-1012, 2006. 3. Gonzalez, P., Garcia-Castro, M., Reguero, J. R., Batalla, A., Ordonez, A. G., Palop, R. L., Lozano, I., Montes, M., Alvarez, V., Coto, E. The pro279leu variant in the transcription factor MEF2A is associated with myocardial infarction. (Letter) J. Med. Genet. 43: 167-169, 2006.
• Gene Name
  MEF2A
• Protein Name
  Myocyte-specific enhancer factor 2A
• Gene Full Name
  myocyte enhancer factor 2A
• Synonyms
  ADCAD1 | MEF 2A | MEF2 | MEF2A | myocyte enhancer factor 2A | Myocyte-specific enhancer factor 2A | RSRFC4 | RSRFC9 | Q02078
• Uniprot ID
  Q02078
• Entrez GeneID
  4205
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEF2A  
• Gene symbol
  MEF2A
• Short name
  MEF2A Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  myocyte enhancer factor 2A (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  myocyte enhancer factor 2A, ADCAD1 and mef2 and RSRFC4 and RSRFC9, MEF2A and IDBG-31725 and ENSG00000068305 and 4205, protein dimerization activity, nuclei, Mef2a and IDBG-192076 and ENSMUSG00000030557 and 17258, MEF2A and IDBG-628642 and ENSBTAG00000010649 and 407231

Gene info

• Identity
  HGNC:6993
• Gene
  MEF2A
• Long gene name
  myocyte enhancer factor 2A
• Synonyms
  • RSRFC4
  • RSRFC9
• Locus
  15q26.3
• Discovery year
  1995-02-08
• Entrez gene record
  4205
• Pubmed identfication
  • 1516833
• Classification
  • Myocyte enhancer factor 2 proteins
  • MADS box family
• VEGA ID
  OTTHUMG00000171937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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