MEF2A Antibody

• Catalog number
  R30921
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MEF2A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the MEF2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MEF2A antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q02078
• Purity
  Antigen affinity
• Description
  Myocyte enhancer factor 2A, also known as RSRFC4, RSRFC9, is a protein that in humans is encoded by the MEF2A gene. It is atranscription factorin the Mef2 family. Several alternative splice variants of MEF2A were identified that were predicted to encode different protein products. Using immunofluorescence, MEF2A protein was detected in the nuclei of skeletal and cardiac muscle cells. The gene is mapped on 15q26.3. MEF2A may be involved in induction of muscle differentiation and MEF2C in maintenance of the differentiated state. Coimmunoprecipitation assays indicated that GEF bound both MEF2A and MEF2D in vitro, and MEF2D interfered with the transcriptional activation promoted by the cooperative interaction of MEF2A and GEF. A transcriptional repressor form of MEF2A that is sumoylated at lys403 promoted dendritic claw differentiation.
• Immunogen
  An amino acid sequence from the C-terminus of human Myocyte enhancer factor 2A (MLSLGQVSAWQQHHLGQ) was used as the immunogen for this MEF2A antibody.
• Storage
  After reconstitution, the MEF2A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEF2A  
• Gene symbol
  MEF2A
• Short name
  Anti-MEF2A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to MEF2A
• Alternative technique
  antibodies
• Alternative to gene target
  myocyte enhancer factor 2A, ADCAD1 and mef2 and RSRFC4 and RSRFC9, MEF2A and IDBG-31725 and ENSG00000068305 and 4205, protein dimerization activity, nuclei, Mef2a and IDBG-192076 and ENSMUSG00000030557 and 17258, MEF2A and IDBG-628642 and ENSBTAG00000010649 and 407231

Gene info

• Identity
  HGNC:6993
• Gene
  MEF2A
• Long gene name
  myocyte enhancer factor 2A
• Synonyms
  • RSRFC4
  • RSRFC9
• Locus
  15q26.3
• Discovery year
  1995-02-08
• Entrez gene record
  4205
• Pubmed identfication
  • 1516833
• Classification
  • Myocyte enhancer factor 2 proteins
  • MADS box family
• VEGA ID
  OTTHUMG00000171937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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