E2F3 Antibody
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Catalog numberA03068
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PricePlease ask
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Size0,1 mg
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Target antigenE2F3
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with speciesmouse, rat
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AnalysesWB
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ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human E2F3 (278-320aa QSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKA), identical to the related mouse sequence.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the E2F3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe E2F3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundTranscription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.
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Related articles1. Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G., Bremner, R. Division and apoptosis of E2f-deficient retinal progenitors. Nature 462: 925-929, 2009. 2. Chong, J.-L., Wenzel, P. L., Saenz-Robles, M. T., Nair, V., Ferrey, A., Hagan, J. P., Gomez, Y. M., Sharma, N., Chen, H.-Z., Ouseph, M., Wang, S.-H., Trikha, P., and 10 others. E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature 462: 930-934, 2009.
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Gene NameE2F3
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Protein NameTranscription factor E2F3
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Gene Full NameE2F transcription factor 3
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SynonymsE2F3 | E2F-3 | KIAA0075 | Transcription factor E2F3 | O00716
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Uniprot IDO00716
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Entrez GeneID1871
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolE2F3, E2F3-IT1
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Short nameE2F3 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameE2F3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameE2F transcription factor 3
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GenBank acession
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Locus
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Discovery year1994-08-31
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Entrez gene record
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Pubmed identfication
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Classification
- E2F transcription factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameE2F3 intronic transcript 1
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Synonyms gene name
- E2F3 intronic transcript 1 (non-protein coding)
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Locus
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Discovery year2011-05-24
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Classification
- Intronic transcripts
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data