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Target antigen
BCA1
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, rat
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Analyses
WB,IHC-P,ELISA
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Immunogen
E. coli-derived human BCA1 recombinant protein (Position: V23-P109). Human BCA1 shares 45.3% amino acid (aa) sequence identity with mouse BCA1.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the BCA1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The BCA1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
C-X-C motif chemokine 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC), is a protein that in humans is encoded by the CXCL13 gene. CXCL13 is a small cytokine belonging to the CXC chemokine family. Its gene is mapped to human chromosome 4 in a cluster of other CXC chemokines. This protein has contained 109 amino acids. It is expressed highly in the liver, spleen, lymph nodes and gut of humans. The protein induces chemotaxis of BLR1-expressing B cells.
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Related articles
1. Ansel, K. M., Harris, R. B. S., Cyster, J. G. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 16: 67-76, 2002. 2. Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT (February 1998). "A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1". Nature 391 (6669): 799–803. 3. Legler DF, Loetscher M, Roos RS, Clark-Lewis I, Baggiolini M, Moser B (February 1998). "B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5". J. Exp. Med. 187 (4): 655–60.
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Gene Name
CXCL13
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Protein Name
C-X-C motif chemokine 13
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Gene Full Name
chemokine (C-X-C motif) ligand 13
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Synonyms
ANGIE antibody|ANGIE2 antibody|B cell attracting chemokine 1 antibody|B cell-attracting chemokine 1 antibody|B lymphocyte chemoattractant antibody|B-cell chemoattractant antibody| B-cell-attracting chemokine 1 antibody|BCA-1 antibody|BLC antibody|BLR1L antibody| C-X-C motif chemokine 13 antibody|Chemokine (C-X-C motif) ligand 13 antibody| Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) antibody|Chemokine, CXC motif, ligand 13 antibody|CXC chemokine BLC antibody|CXCL13 antibody|CXL13_HUMAN antibody|SCYB13 antibody| Small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant) antibody|Small inducible cytokine B13 antibody|Small inducible cytokine subfamily B, member 13 antibody|Small-inducible cytokine B13 antibody
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Uniprot ID
O43927
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Entrez GeneID
10563
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
