Recombinant Cynomolgus Programmed cell death ligand 2/PD-L2(C-Fc)

Alternative names

Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Description

Recombinant Cynomolgus monkey Programmed cell death ligand 2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a Fc tag at the C-terminus.
Expression

Human Cells
Tag

C-Fc
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

A4GW30
TargetSequence

Leu20-Pro219
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Note

For research use only.
Additional description

For cells, cell lines and tissues in culture till half confluency. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Cynomolgus Programmed death ligand 2/PD-L2 C-Fc
Gene symbol

PDCD1LG2, MRPL37, ENPP2, KLK5, PPFIBP1, MICALL2, ZACN, PDCD1, ENPP3, GLDN
Short name

Recombinant Cynomolgus Programmed death ligand 2/PD-L2(C-Fc)
Technique

Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Cynomolgus
Alternative name

Rec. Cynomolgus Programmed cellular death ligand 2/PD-L2(C-fragment c)
Alternative technique

rec
Tissue

cell

Identity

HGNC:18731
Gene

PDCD1LG2
Long gene name

programmed cell death 1 ligand 2
Synonyms
- PD-L2
- Btdc
- PDL2
- bA574F11.2
- CD273
- B7-DC
Synonyms name
- B7 dendritic cell molecule
GenBank acession
- AF344424
Locus

9p24.1
Discovery year

2003-11-14
Entrez gene record

80380
Pubmed identfication
- 11224527
RefSeq identity
- NM_025239
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000019504

Identity

HGNC:14034
Gene

MRPL37
Long gene name

mitochondrial ribosomal protein L37
Synonyms
- RPML2
- MRP-L2
GenBank acession
- AB051344
Locus

1p32.3
Discovery year

2001-02-28
Entrez gene record

51253
Pubmed identfication
- 10600119
RefSeq identity
- NM_016491
Classification
- Large subunit mitochondrial ribosomal proteins
- Mitochondrial ribosomal proteins
VEGA ID

OTTHUMG00000008118

Identity

HGNC:9249
Gene

PPFIBP1
Long gene name

PPFIA binding protein 1
Synonyms gene name
- PTPRF interacting protein, binding protein 1 (liprin beta 1)
Synonyms
- L2
- hSGT2
- hSgt2p
- SGT2
Synonyms name
- liprin beta 1
GenBank acession
- AF034802
Locus

12p11.23-p11.22
Discovery year

1998-10-23
Entrez gene record

8496
Pubmed identfication
- 9624153
- 11836260
RefSeq identity
- NM_003622
Classification
- Sterile alpha motif domain containing
VEGA ID

OTTHUMG00000169207

Identity

HGNC:29504
Gene

ZACN
Long gene name

zinc activated ion channel
Synonyms gene
- LGICZ1
Synonyms gene name
- ligand-gated ion channel, zinc activated 1
- zinc activated ligand-gated ion channel
Synonyms
- LGICZ
- L2
- ZAC
- ZAC1
GenBank acession
- AK122638
Locus

17q25.1
Discovery year

2006-01-31
Entrez gene record

353174
Pubmed identfication
- 12381728
- 16083862
RefSeq identity
- NM_180990
Classification
- Zinc activated channels
VEGA ID

OTTHUMG00000157186

Identity

HGNC:3358
Gene

ENPP3
Long gene name

ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms gene
- PDNP3
Synonyms
- PD-IBETA
- gp130RB13-6
- B10
- CD203c
GenBank acession
- AF005632
Locus

6q23.2
Discovery year

1995-08-10
Entrez gene record

5169
Pubmed identfication
- 9344668
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
VEGA ID

OTTHUMG00000016292

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data