YM201636

• Catalog number
  2045-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3′2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide
• Description
  Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110α at higher concentration (IC50 = 3 µM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells.
• CAS Number
  371942-69-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₂₁N₇O₃
• Molecular Weight
  467.49
• Cell Permeable
  Yes
• Purity
  ≥98% by NMR
• Solubilities
  DMSO or EtOH
• Handling
  Protect from air and light
• Tag Line
  A PIKfyve inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD16038303
• PubChem CID
  9956222
• PubChem CID Link
• SMILES
  C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
• InChi
  InChI=1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17) 22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8, 13-14H,9-12H2,(H2,26,28)(H,29,33)
• InChi Key
  YBPIBGNBHHGLEB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  YM201636  
• Short name
  YM201636
• Alternative name
  YM201636

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