Talabostat mesylate

• Catalog number
  B2061-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid methanesulfonic acid ; PT-100; Val-boro-pro
• Description
  Talabostat is a nonselective inhibitor of post-proline cleaving serine proteases. The inhibition of the highly related cytosolic serine proteases Dpp8 and Dpp9 (Dpp8/9) by Val-boroPro was recently demonstrated to trigger an immunostimulatory form of programmed cell death known as pyroptosis selectively in monocytes and macrophages. Talabostat induces powerful anti-tumor immune responses in syngeneic cancer models.
• CAS Number
  150080-09-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₂₃BN₂OS
• Molecular Weight
  310.17
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and moisture
• Tag Line
  A nonselective inhibitor of post-proline cleaving serine proteases
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11522448
• PubChem CID Link
• SMILES
  B(C1CCCN1C(=O)C(C(C)C)N)(O)O.CS(=O)(=O)O
• InChi
  InChI=1S/C9H19BN2O3.CH4O3S/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15;1-5(2,3)4/h6-8,14-15H,3-5,11H2,1-2H3;1H3,(H,2,3,4)/t7-,8-;/m0./s1
• InChi Key
  OXYYOEIGQRXGPI-WSZWBAFRSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Talabostat   mesylate  
• Short name
  Talabostat mesylate
• Alternative name
  Talabostat mesylate

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