SCR7 pyrazine

  • Catalog number
    B1119-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone
  • Description
    SCR7 pyrazine is a potent inhibitor of nonhomologous endjoining (NHEJ) mediated by DNA ligase IV. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.
  • CAS Number
    14892-97-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₈H₁₂N₄OS
  • Molecular Weight
    332.38
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A DNA ligase IV inhibitor and HDR enhancer
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD02167478
  • PubChem CID
    10688007
  • SMILES
    C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
  • InChi
    InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
  • InChi Key
    GSRTWXVBHGOUBU-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    SCR7   pyrazine  
  • Short name
    SCR7 pyrazine
  • Alternative name
    SCR7 pyrazine
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