SCR7 pyrazine
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Catalog numberB1119-5
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PricePlease ask
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Size5 mg
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Alternative_name2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone
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DescriptionSCR7 pyrazine is a potent inhibitor of nonhomologous endjoining (NHEJ) mediated by DNA ligase IV. Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro.
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CAS Number14892-97-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₈H₁₂N₄OS
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Molecular Weight332.38
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml)
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HandlingProtect from air and light
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Tag LineA DNA ligase IV inhibitor and HDR enhancer
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD02167478
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PubChem CID10688007
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SMILESC1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
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InChiInChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
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InChi KeyGSRTWXVBHGOUBU-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameSCR7 pyrazine
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Alternative nameSCR7 pyrazine
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