SC66

• Catalog number
  1870-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  (2E, 6E)-2, 6-Bis(pyridine-4ylmethylene)cyclohexanone
• Description
  Cell-permeable. An allosteic Akt inhibitor that directly facilitates Akt ubiquitination in vitro and in vivo. SC66 displays a dual inhibitory activity that directly interferes with the pleckstrin homology (PH) domain binding to PIP₃ and facilitates Akt ubiquitination. Due to its dual inhibitory activity, SC66 displays a more effective growth suppression of transformed cells that contain a high level of Akt signaling, compared with other inhibitors of PIP₃/Akt pathway.
• CAS Number
  871361-88-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₆N₂O
• Molecular Weight
  276.33
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An allosteric Akt inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD05025493
• PubChem CID
  6018993
• PubChem CID Link
• SMILES
  C1CC(=CC2=CC=NC=C2)C(=O)C(=CC3=CC=NC=C3)C1
• InChi
  InChI=1S/C18H16N2O/c21-18-16(12-14-4-8-19-9-5-14)2-1-3-17(18)13-15-6-10-20-11-7-15/h4-13H,1-3H2/b16-12+,17-13+
• InChi Key
  CYVVJSKZRBZHAV-UNZYHPAISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SC66  
• Short name
  SC66
• Alternative name
  SC66

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