L-Buthionine-(S,R)-Sulfoximine

• Catalog number
  B2305-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  α-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thiopheneacetamide
• Description
  L-Buthionine-(S,R)-Sulfoximine is a potent, fast acting, irreversible inhibitor of gamma-glutamylcysteine synthetase the rate-limiting enzyme for L-glutathione (GSH) synthesis, that induces oxidative stress in cells by depleting GSH. Shown to improve the outcome of chemotherapy by lowering the levels of glutathione in cancer cells.
• CAS Number
  83730-53-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₈H₁₈N₂O₃S
• Molecular Weight
  222.3
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  PBS, pH 7.2 (~5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, fast acting, irreversible inhibitor of gamma-glutamylcysteine synthetase
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00067000
• PubChem CID
  119565
• PubChem CID Link
• SMILES
  CCCCS(=N)(=O)CCC(C(=O)O)N
• InChi
  InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
• InChi Key
  KJQFBVYMGADDTQ-CVSPRKDYSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  L-Buthionine   Sulfoximine  
• Short name
  L-Buthionine-(S R)-Sulfoximine
• Alternative name
  L-Buthionine-(S,R)-Sulfoximine

Product images

Similar products