K252a
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Catalog number2013-500
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PricePlease ask
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Size500 ug
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Alternative_nameSF 2370
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DescriptionAn analog of Staurosporine (Cat. No. 1048) that acts as a non-selective protein kinase inhibitor. Iinhibits PKA (Ki = 18 nM), PKC (Ki = 25 nM), and PKG (Ki = 20 nM). Potently inhibits CaMK (Ki = 1.8 nM), competitively with ATP and noncompetitively with the substrate.
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CAS Number99533-80-9
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₇H₂₁N₃O₅
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Molecular Weight467.47
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (100 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective protein kinase inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00161522
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PubChem CID127357
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SMILESCC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O
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InChiInChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27?/m1/s1
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InChi KeyKOZFSFOOLUUIGY-UHOLRESSSA-N
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MSDS AvailableYes
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Gene target
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Short nameK252a
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Alternative nameK252a
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