Human XAF1 protein

Synonyms

XIAP associated factor 1 isoform 1, BIRC4-binding protein, XAF1
Alternative_names

XIAP associated factor 1 isoform 1, BIRC4-binding protein, XAF1
Description

A negative regulator of the members of the IAP
Recombinant

YES
Source

E.coli
Purity by SDS PAGE

>90% by SDS-PAGE
Molecular Weight

18.6 kDa (161aa)
Storage Temp

-20°C
Shipping

Gel Pack
Shelf Life

12 months
Concentration

1 mg/ml
Appearance

Liquid
Physical form description

Liquid
Background Information

XAF1 is a negative regulator of the members of the IAP (inhibitor of apoptosis) protein family. It inhibits the anti-caspase activity of BIRC4 (XIAP or IAP3) and enhances apoptosis. It mediates TNF-alpha-induced apoptosis and is involved in apoptosis in trophoblast cells.
Amino acid sequence

1-125 aa
Handling

Centrifuge the vial prior to opening.
Usage

For Research Use Only! Not to be used in humans
Datasheet
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

XAF1 protein
Gene symbol

XAF1
Short name

XAF1 protein
Species

Human, Humans
Alternative name

H. sapiens X-linked inhibitor on apoptosis associated factor 1 protein
Alternative to gene target

XIAP associated factor 1, XAF1 and IDBG-22619 and ENSG00000132530 and 54739, zinc ion binding, nuclei, Xaf1 and IDBG-196515 and ENSMUSG00000040483 and 327959, XAF1 and IDBG-633696 and ENSBTAG00000011343 and 509740