Human CellExp™ Beta 2 Microglobulin
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Catalog number
P1611-10
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Price
Please ask
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Size
10 ug
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Synonyms
B2M
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Alternative_names
B2M
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Description
A component of the class I major histocompatibility complex
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Recombinant
1
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Source
HEK293 cells
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Purity by SDS PAGE
≥ 97% by SDSPAGE
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Endotoxin Level
< 0.1 EU/ug of the protein as determined by LAL method
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Molecular Weight
The protein migrates as a ~12-13 kDa band in SDS-PAGE
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized protein
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Physical form description
Lyophilized protein
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Reconstitution Instructions
Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.
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Background Information
Beta 2 Microglobulin is a component of the class I major histocompatibility complex (MHC). It presents the antigenic peptides to the immune system. It is present in small amounts in serum, csf, and urine of normal people and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure or kidney transplants. The levels of Beta 2 Microglobulin are increased in multiple myeloma. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions.
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Amino acid sequence
aa Ile21-Met119
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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