GNF-5837
-
Catalog numberB1339-5
-
PricePlease ask
-
Size5 mg
-
-
Alternative_name(Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylphenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
-
DescriptionA potent and selective pan-TRK inhibitor, suppressing the activity of TrkA and TrkB with IC50 of 8 and 12 nM, respectively
-
CAS Number1033769-28-6
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC28H21F4N5O2
-
Molecular Weight535.49
-
Cell PermeableYes
-
Purity>98% by HPLC
-
SolubilitiesDMSO > 10 mM
-
HandlingProtect from air and light
-
Tag LineA potent and selective pan-TRK inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
MDL NumberMFCD24386809
-
PubChem CID59397065
-
SMILESCC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)C(=CC5=CC=CN5)C(=O)N4
-
InChi1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12-
-
InChi KeyYYDUWLSETXNJJT-MTJSOVHGSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameGNF-5837
-
Alternative nameGNF-5837
-