anti-TCTN3 Antibody

  • Catalog number
    5837
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    TCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
  • Gene names
    TCTN3 Antibody: OFD4, TECT3, JBTS18, C10orf61, PSEC0041, UNQ1881/PRO4324, Tectonic-3
  • Antibodie s label
    unlabelled serum
  • Purity
    TCTN3 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    TCTN3 antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
  • Antibody advice
    TCTN3 antibody can be used for detection of TCTN3 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 4 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    TCTN3 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    TCTN3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    221136774
  • Ncbi nr
    NP_056446
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    26123
  • GENE symbol
    TCTN3
  • Antigene name
    tectonic family member 3
  • Source
    Homo sapiens
  • Protein nr
    Q6NUS6
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TCTN3  
  • Gene symbol
    TCTN3
  • Short name
    anti-TCTN3 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toTCTN3 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    tectonic family member 3, TCTN3 and IDBG-83525 and ENSG00000119977 and 26123, protein binding, Plasma membranes, Tctn3 and IDBG-164998 and ENSMUSG00000025008 and 67590, TCTN3 and IDBG-637977 and ENSBTAG00000011841 and 511035
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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