anti-TCTN3 Antibody
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Catalog number5837
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
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Gene namesTCTN3 Antibody: OFD4, TECT3, JBTS18, C10orf61, PSEC0041, UNQ1881/PRO4324, Tectonic-3
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Antibodie s labelunlabelled serum
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PurityTCTN3 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTCTN3 antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceTCTN3 antibody can be used for detection of TCTN3 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 4 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideTCTN3 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTCTN3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr221136774
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Ncbi nrNP_056446
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr26123
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GENE symbolTCTN3
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Antigene nametectonic family member 3
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SourceHomo sapiens
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Protein nrQ6NUS6
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTCTN3
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Short nameanti-TCTN3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTCTN3 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targettectonic family member 3, TCTN3 and IDBG-83525 and ENSG00000119977 and 26123, protein binding, Plasma membranes, Tctn3 and IDBG-164998 and ENSMUSG00000025008 and 67590, TCTN3 and IDBG-637977 and ENSBTAG00000011841 and 511035
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Gene info
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Identity
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Gene
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Long gene nametectonic family member 3
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Synonyms gene
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Synonyms gene name
- chromosome 10 open reading frame 61
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-05-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tectonic proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data