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Alternative_name
NSC 141046,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
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Description
Clofazimine is used as an antileprosy drug. It is used to treat multidrug-resistant tuberculosis. Clofazimine prevents neutrophil motility and lymphocyte transformation. It displays anti-inflammatory effect, which is used to treat discoid lupus erythematosus. Clofazimine specifically inhibits canonical Wnt signaling in a panel of TNBC cells in vitro. Clofazimine also displays immunosuppressive property.
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CAS Number
2030-63-9
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₇H₂₂Cl₂N₄
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Molecular Weight
473.4
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Cell Permeable
1
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Purity
≥98% by HPLC
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Solubilities
~ 1 mg/ml DMSO
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
An antimycobacterial compound
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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MDL Number
MFCD00056793
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PubChem CID
2794
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SMILES
CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl
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InChi
InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3
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InChi Key
WDQPAMHFFCXSNU-UHFFFAOYSA-N
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MSDS Available
1