Clofazimine

  • Catalog number
    B2712-250
  • Price
    Please ask
  • Size
    250 mg
  • Alternative_name
    NSC 141046,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
  • Description
    Clofazimine is used as an antileprosy drug. It is used to treat multidrug-resistant tuberculosis. Clofazimine prevents neutrophil motility and lymphocyte transformation. It displays anti-inflammatory effect, which is used to treat discoid lupus erythematosus. Clofazimine specifically inhibits canonical Wnt signaling in a panel of TNBC cells in vitro. Clofazimine also displays immunosuppressive property.
  • CAS Number
    2030-63-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₇H₂₂Cl₂N₄
  • Molecular Weight
    473.4
  • Cell Permeable
    1
  • Purity
    ≥98% by HPLC
  • Solubilities
    ~ 1 mg/ml DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    An antimycobacterial compound
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00056793
  • PubChem CID
    2794
  • SMILES
    CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl
  • InChi
    InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3
  • InChi Key
    WDQPAMHFFCXSNU-UHFFFAOYSA-N
  • MSDS Available
    1
  • Gene target
  • Short name
    Clofazimine
  • Alternative name
    Clofazimine
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