CH5183284

• Catalog number
  B1649-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  CH5183284; CH-5183284; CH 5183284; Debio-1347; Debio 1347; Debio1347; FF284; FF-284; FF 284; (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone
• Description
  CH5183284 is a selective and orally available FGFR1/2/3 inhibitor. The IC50 values of CH5183284 on the enzyme activity of FGFR1/2/3/4 were 9.3, 7.6, 22, and 290 nM, respectively.
• CAS Number
  1265229-25-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₁₆N₆O
• Molecular Weight
  356.38
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, selective inhibitor of the kinase activity of FGFRs
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  NA
• PubChem CID
  66555680
• PubChem CID Link
• SMILES
  CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
• InChi
  InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
• InChi Key
  BEMNJULZEQTDJY-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CH5183284  
• Short name
  CH5183284
• Alternative name
  CH5183284

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