Cardiolipin Assay Kit (Fluorometric)

  • Catalog number
    K944-100
  • Price
    Please ask
  • Size
    100 assays
  • Description
    The easiest kit in the market to measure Cardiolipin in samples
  • Summary
    • Detection method- Fluorescence (Ez/Em 340/480 nm) • Sample type- Cell lysate and mitochondria • Species reactivity- Mammalian • Applications- This assay provides a convenient and non-ELISA alternative to detect cardiolipin amount in biological samples.
  • Detection Method
    Fluorescence (Ex/Em 340/480 nm)
  • Species Reactivity
    Mammalian
  • Applications
    This assay provides a convenient and non-ELISA alternative to detect cardiolipin amount in biological samples.
  • Sample Type
    Cell lysate and mitochondria
  • Features Benefits
    Simple, fast, does not require lenghty incubation times
  • Storage Conditions
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf life
    12 months
  • Background
    Cardiolipin (CL) is a very important phospholipid present in the inner mitochondrial membrane and constitutes about 20% of its total lipid composition. It has a dimeric structure comprised of two phosphatidic acid residues linked by a glycerol bridge. It is essential for several mitochondrial functions such as maintaining activity of the electron transport chain complexes, and other mitochondrial processes including biogenesis, fission, fusion and protein transport. It is involved in apoptosis where it helps alter the mitochondrial membrane structure and aids in the release of cytochrome c. Condition such as diabetes and heart failure are linked to changes in levels of cardiolipin and it is also depleted during aging. Exposure to toxicants like cigarette smoke and organophosphates may cause an alteration in cardiolipin levels and composition, thus adversely affecting health. BioVision’s Cardiolipin Assay is a fluorometric assay that makes use of a proprietary probe that fluoresces on association with cardiolipin but not with any other lipids such as phosphatidylcholine and sphingomyelin, making it highly specific. Fluorescence can be recorded at Ex/Em 340/480 nm. The kit includes purified cardiolipin as standard and can detect as low as 0.2 nmol of cardiolipin
  • Test
    Biovision supplies other types of Assays as 1.
  • Gene target
  • Short name
    Cardiolipin Assay Kit (Fluorometric)
  • Technique
    Assay, assays
  • Host
    Assay
  • Alternative name
    Cardiolipin test reagent (fluorescence)
  • Alternative technique
    arrays, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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