Butyrolactone I
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Catalog number1690-200
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PricePlease ask
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Size200 ug
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Alternative_nameBLI, BL-I
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DescriptionCell permeable. A potent and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. BLI is an important tool for probing the cellular roles of CDKs. It blocks Fas-induced apoptosis and displays antitumor activity.
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CAS Number87414-49-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₄O₇
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Molecular Weight424.44
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Cell PermeableYes
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Purity≥99% by HPLC
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SolubilitiesDMSO (10 mg/ml) and Ethanol (25 mg/ml)
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HandlingProtect from air and light
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Tag LineA CDK inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD03453074
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PubChem CID3035414
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SMILESCC(=CCC1=C(C=CC(=C1)COC(=O)C2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C)O)C
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InChiInChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-30-23(29)24(3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2, 1-3H3/t24-/m1/s1
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InChi KeyFPVUCBMBMUHRDX-XMMPIXPASA-N
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MSDS AvailableYes
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Gene target
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Short nameButyrolactone I
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Alternative nameButyrolactone I
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