Butyrolactone I

  • Catalog number
    1690-200
  • Price
    Please ask
  • Size
    200 ug
  • Alternative_name
    BLI, BL-I
  • Description
    Cell permeable. A potent and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. BLI is an important tool for probing the cellular roles of CDKs. It blocks Fas-induced apoptosis and displays antitumor activity.
  • CAS Number
    87414-49-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₄O₇
  • Molecular Weight
    424.44
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO (10 mg/ml) and Ethanol (25 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A CDK inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD03453074
  • PubChem CID
    3035414
  • SMILES
    CC(=CCC1=C(C=CC(=C1)COC(=O)C2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C)O)C
  • InChi
    InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-30-23(29)24(3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2, 1-3H3/t24-/m1/s1
  • InChi Key
    FPVUCBMBMUHRDX-XMMPIXPASA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Butyrolactone I
  • Alternative name
    Butyrolactone I
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