Brivanib Alaninate

  • Catalog number
    B1326-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate; BMS-582664
  • Description
    Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.
  • CAS Number
    649735-63-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₂₄FN₅O₄
  • Molecular Weight
    441.46
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>40 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    ATP-competitive inhibitor of VEGFR2 with anticancer properties
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    11154925
  • SMILES
    CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C
  • InChi
    InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1
  • InChi Key
    LTEJRLHKIYCEOX-OCCSQVGLSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Brivanib Alaninate
  • Alternative name
    Brivanib Alaninate
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