Brivanib

• Catalog number
  B1325-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (R)-1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-ol; BMS-540215
• Description
  Brivanib is a potent, ATP-competitive inhibitor against human Flk-1 (VEGFR-2) and mouse Flk-1 with IC₅₀ of 25 nM and 89 nM, respectively. Brivanib also inhibits VEGFR-1 and FGFR-1 with IC₅₀ values of 0.38 and 0.148 μM. Brivanib displays antitumor activities in H3396 xenograft.
• CAS Number
  649735-46-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₉FN₄O₃
• Molecular Weight
  370.38
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, ATP-competitive inhibitor against human Flk-1 (VEGFR-2) and mouse Flk-1
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11234052
• PubChem CID Link
• SMILES
  CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C
• InChi
  InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1
• InChi Key
  WCWUXEGQKLTGDX-LLVKDONJSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Brivanib  
• Short name
  Brivanib
• Alternative name
  Brivanib

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