AT9283

• Catalog number
  2432-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
• Description
  A pan-Aurora kinase inhibitor (IC₅₀ = 3 nM for both Aurora A and B). AT9283 also potently inhibits several kinases including the JAK2 and 3 (IC₅₀’s 1.2 and 1.1 nM, respectively), c-Abl(IC₅₀ = 110 nM) and Abl/T315I (IC₅₀ = 4 nM).
• CAS Number
  896466-04-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₂₃N₇O₂
• Molecular Weight
  381.43
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>70 mg/ml) or EtOH (>25 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A multi-targeted c-Abl, JAK2, Aurora A and B inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11696609
• PubChem CID Link
• SMILES
  C1CC1NC(=O)NC2=CNNC2=C3N=C4C=CC(=CC4=N3)CN5CCOCC5
• InChi
  InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13,20,25H,2-3,5-8,11H2,(H2,21,24,27)/b18-17-
• InChi Key
  VRXXZJLHPWWXIX-ZCXUNETKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AT9283  
• Short name
  AT9283
• Alternative name
  AT9283

Similar products