Arecoline hydrobromide
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Catalog numberB1824-100
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PricePlease ask
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Size100 mg
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Alternative_name1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, hydrobromide
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DescriptionArecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC₅₀ = 11.1 μM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. Agonist at muscarinic acetylcholine receptors M1 – M5 (EC₅₀ in the range of 7-410 nM). May be effective in dementia.
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CAS Number300-08-3
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Structure AvailableYes
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Molecular FormulaC₈H₁₃NO₂ • HBr
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Molecular Weight236.11
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Cell PermeableYes
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Purity≥98% by TLC
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SolubilitiesH₂O (>50 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA covalent ACAT1 inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00039041
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PubChem CID9301
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SMILESCN1CCC=C(C1)C(=O)OC.Br
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InChiInChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H
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InChi KeyAXOJRQLKMVSHHZ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameArecoline hydrobromide
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Alternative nameArecoline hydrobromide
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