Arecoline hydrobromide

• Catalog number
  B1824-500
• Price
  Please ask
• Size
  500 mg

• Alternative_name
  1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, hydrobromide
• Description
  Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC₅₀ = 11.1 μM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. Agonist at muscarinic acetylcholine receptors M1 – M5 (EC₅₀ in the range of 7-410 nM). May be effective in dementia.
• CAS Number
  300-08-3
• Structure Available
  Yes
• Molecular Formula
  C₈H₁₃NO₂ • HBr
• Molecular Weight
  236.11
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  H₂O (>50 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A covalent ACAT1 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00039041
• PubChem CID
  9301
• PubChem CID Link
• SMILES
  CN1CCC=C(C1)C(=O)OC.Br
• InChi
  InChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H
• InChi Key
  AXOJRQLKMVSHHZ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Arecoline   hydrobromide  
• Short name
  Arecoline hydrobromide
• Alternative name
  Arecoline hydrobromide

Product images

Similar products