ACE1 Colorimetric Activity Assay Kit
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Catalog number
K2001-100
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Price
Please ask
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Size
100 assays
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Description
to detect ACE1 activity in a variety of samples
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Summary
BioVision’s ACE1 Activity Assay Kit can be used to detect its activity in biological samples. This kit utilizes the ability of an active ACE1 to hydrolyze a synthetic substrate, which results in the decrease in optical density at 345 nm. The assay kit provides a rapid, simple and sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples.
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Detection Method
Absorbance, OD 345 nm
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Species Reactivity
All
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Applications
Measurement of ACE1 activity in Plasma or Serum samples
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Sample Type
Plasma, Serum
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Features Benefits
Simple, Rapid, Sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples
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Storage Conditions
-20°C
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Shipping Conditions
Gel Pack
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Shelf life
12 months
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Background
Angiotensin-I-converting enzyme (ACE1) is a peptidyl dipeptidase that catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II, by removing a carboxy-terminal dipeptide. ACE is a key part of the renin angiotensin system (RAS) that regulates blood pressure. Increased ACE activity leads to an increase in the angiotensin II (Ang II) levels. This may increase the risk of developing neurodegenerative diseases including Parkinson, Alzheimer, Huntington, Multiple Sclerosis etc. Elevated levels of Ang II mediate cardiac remodeling (cardiac hypertrophy and fibrosis), which is a hallmark in heart failure. Previous researchers have shown that ACE activity is a better predictor of pathologies associated with Type 2 diabetes than ACE levels in serum samples. BioVision’s ACE1 Activity Assay Kit can be used to detect its activity in biological samples. This kit utilizes the ability of an active ACE1 to hydrolyze a synthetic substrate, which results in the decrease in optical density at 345 nm. The assay kit provides a rapid, simple and sensitive method to detect ACE1 activity as low as 40 mU in a variety of samples.
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Test
Biovision supplies other types of Assays as 1.
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Properties
Colorimetric assays or detection use UV absorption or enzymatic color reaction.
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Gene target
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Gene symbol
ACE
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Short name
ACE1 Colorimetric Activity Assay Kit
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Technique
colorimetric, Assay, assays, colorimetry
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Host
Assay
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Alternative name
ACE1 colorimetry Activity test reagent
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Alternative technique
assays, arrays, kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
Product images
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