MMP 17 (MT4-MMP) catalytic domain, His-tagged (Recombinant Protein)
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Catalog number30 100 403
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PricePlease ask
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Size200 µg/ 1 ml
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Protein typeRecombinant
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Protein subtypeEC 3.4.24.-
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Protein familyMatrix Metalloproteinases, matrixins
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Protein descriptionMMP17 is a endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
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Research area interestsAmong MMP17 related pathways are Matrix Metalloproteinases and Degradation of the extracellular matrix.
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Package formliquid
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Tested applicationsDegradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard
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Other namesMembrane-Type 4 Matrix Metalloproteinase
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Peptide sequenceQ A P A P T K W N K R N L S W R V R T F P R D S P L G H D T V R A L M Y Y A L R V W S D I A P L N F H E V A G S T A D I Q I D L S K A D H N D G Y P F D G P G G T V A H A F F P G H H H T A G D T H F D D D E A W T F R S S D A H G M D L F A V A V H E F G H A I G L S H V A A A H S I M R P Y Y Q G P V G D P L R Y G L P Y E D K V R V W Q L Y G V R E S V S P T A Q P E E P P L E H H H H H H
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Available target modificationNo
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Expression systemE.coli
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Product Subtypeprotein fragment
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Active formYes
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TagHis-tagged
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Contents50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.1% Triton X-100.
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Protein purity0.8
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Molecular weight24 kDa
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UniProt numberQ9ULZ9
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Gene number4326
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AbbreviationMMP17 (partial)
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Full namematrix metallopeptidase 17 (partial)
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Other desciptionThe catalytic domain of human MT4-MMP is produced by tryptic activation of a recombinant soluble proform purified from E. coli periplasm.
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PurificationMentioned in the data sheet
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PubMed citationsSee the data sheet
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WarningsFor Research Use only.
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Shipping conditionsdry ice
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Storage conditionStore at -70°C
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Technical datasheetContact us to receive the datasheet
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Conjugationhistidine
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolMMP17, MMP14, MMP24, MMP28, MMP15, MMP25, MMP16, MT4
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Short nameMMP 17 (MT4-MMP) catalytic domain, His-tagged (Recombinant Protein)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. biotez advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Labelhis-tagged
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SpeciesHomo sapiens
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Alternative nameMMP 17 (MT4-MMP) catalytic domain, histidine-tagged (Rec. Protein)
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 17
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Synonyms gene name
- matrix metalloproteinase 17 (membrane-inserted)
- matrix metallopeptidase 17 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 14
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Synonyms gene name
- matrix metalloproteinase 14 (membrane-inserted)
- matrix metallopeptidase 14 (membrane-inserted)
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-11-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 24
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Synonyms gene name
- matrix metalloproteinase 24 (membrane-inserted)
- matrix metallopeptidase 24 (membrane-inserted)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-08-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 28
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Synonyms gene name
- matrix metalloproteinase 28
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 15
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Synonyms gene name
- matrix metalloproteinase 15 (membrane-inserted)
- matrix metallopeptidase 15 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 25
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 25
- matrix metallopeptidase-like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-12-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 16
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 16 (membrane-inserted)
- chromosome 8 open reading frame 57
- matrix metallopeptidase 16 (membrane-inserted)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemetallothionein 4
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Synonyms gene name
- metallothionein IV
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Metallothioneins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data