TREML2 Antibody

• Catalog number
  bs-2737R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TREML2 Primary Polyclonal Antibody
• Also known as
  TREML2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TREML2
• Specificity
  This is a highly specific antibody against TREML2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TREML2
• Gene ID number
  79865
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  TREML2 is expressed throughout B cell development in addition to being expressed on macrophages and neutrophils and is the only TREM molecule to be found on lymphocytes. TREML2 is expressed on B lineage cells early in development, and the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens. TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain. Thus, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling. Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, but its expression is up-regulated in conjunction with differentiation into macrophages. TREML2 is present on neutrophils in the bone marrow as well as the periphery, and inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo.TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C6orf76; Chromosome 6 open reading frame 76; FLJ13693; MGC149715; MGC149716; TLT 2; TLT2; TREM like transcript 2; Trem like transcript 2 protein; Triggering receptor expressed on myeloid cells like 2; Triggering receptor expressed on myeloid cells like protein 2; TRML2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TREML2  
• Gene symbol
  TREML2
• Short name
  Anti-TREML2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TREML2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  triggering receptor expressed on myeloid cells-like 2, TREML2 and IDBG-86610 and ENSG00000112195 and 79865, protein binding, Cell surfaces, Treml2 and IDBG-189835 and ENSMUSG00000071068 and 328833, TREML2 and IDBG-630865 and ENSBTAG00000015707 and 515548

Gene info

• Identity
  HGNC:21092
• Gene
  TREML2
• Long gene name
  triggering receptor expressed on myeloid cells like 2
• Synonyms gene
  • C6orf76
• Synonyms gene name
  • chromosome 6 open reading frame 76
  • triggering receptor expressed on myeloid cells-like 2
• Synonyms
  • FLJ13693
  • TLT2
  • dJ238O23.1
• Synonyms name
  • TREM-like transcript 2
• GenBank acession
  • AK023755
• Locus
  6p21.1
• Discovery year
  2003-05-19
• Entrez gene record
  79865
• Pubmed identfication
  • 12645956
• RefSeq identity
  • NM_024807
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000016349

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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