TNIK (Ser769) Antibody

• Catalog number
  bs-5599R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TNIK (Ser769) Primary Polyclonal Antibody
• Also known as
  TNIK (Ser769) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TNIK Ser769
• Specificity
  This is a highly specific antibody against TNIK Ser769.
• Modification s
  Phosphorylation
• Modification site s
  Ser769
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  767-774/1360
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser769
• Gene ID number
  23043
• Swiss Prot
  Q9UKE5
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TRAF2 and NCK-interacting protein kinase; TNIK; KIAA0551
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TNIK   Ser769  
• Gene symbol
  TNIK
• Short name
  Anti-TNIK Ser769
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TNIK (Ser769) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  TRAF2 and NCK interacting kinase, TNIK and IDBG-64741 and ENSG00000154310 and 23043, transferase activity, nuclei, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627

Gene info

• Identity
  HGNC:30765
• Gene
  TNIK
• Long gene name
  TRAF2 and NCK interacting kinase
• Synonyms
  • KIAA0551
• GenBank acession
  • AF172264
• Locus
  3q26.2-q26.31
• Discovery year
  2004-02-26
• Entrez gene record
  23043
• Pubmed identfication
  • 9628581
  • 10521462
• RefSeq identity
  • NM_015028
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159036

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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