Rabbit Anti Human TNIK Antibody-Non-conjugated
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Catalog numberCSB-PA023998LA01HU_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Human TNIK, Non-conjugated
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Synonym nameTNIK Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ9UKE5
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human TRAF2 and NCK-interacting protein kinase protein (523-714AA)
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Immunogen speciesHuman
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AliasTRAF2 and NCK-interacting protein kinase,TNIK,KIAA0551
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BackgroundSerine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
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ClonalityPolyclonal antibody
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Shipping and storageTNIK Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenTRAF2 and NCK-interacting protein kinase
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolTNIK
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Short nameAnti-TNIK
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameTNIK Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetTRAF2 and NCK interacting kinase, TNIK and IDBG-64741 and ENSG00000154310 and 23043, transferase activity, nuclei, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627
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Gene info
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Identity
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Gene
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Long gene nameTRAF2 and NCK interacting kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-02-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data