TAB1 Antibody

• Catalog number
  bs-4135R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TAB1 Primary Polyclonal Antibody
• Also known as
  TAB1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TAB1
• Specificity
  This is a highly specific antibody against TAB1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP3K7IP1/TAB1
• Gene ID number
  10454
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1; TAB1; MAP3K7IP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TAB1  
• Gene symbol
  TAB1
• Short name
  Anti-TAB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TAB1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  TGF-beta activated kinase 1/MAP3K7 binding protein 1, 3\'-Tab1 and MAP3K7IP1, TAB1 and IDBG-8281 and ENSG00000100324 and 10454, mitogen-activated protein kinase p38 binding, nuclei, Tab1 and IDBG-163423 and ENSMUSG00000022414 and 66513, MAP3K7IP1 and IDBG-641725 and ENSBTAG00000019828 and 519958

Gene info

• Identity
  HGNC:18157
• Gene
  TAB1
• Long gene name
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
• Synonyms gene
  • MAP3K7IP1
• Synonyms gene name
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 1
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1
• Synonyms name
  • TAK1-binding protein 1
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 1
• GenBank acession
  • U49928
• Locus
  22q13.1
• Discovery year
  2002-02-22
• Entrez gene record
  10454
• Pubmed identfication
  • 8638164
  • 10187861
• RefSeq identity
  • NM_153497
• VEGA ID
  OTTHUMG00000151102

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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