SRC (17AT28) Monoclonal Antibody
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Catalog numberbsm-51271M
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Price:
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Size0.1ml
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Long nameSRC (17AT28) Monoclonal Antibody
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Also known asSRC (17AT28) Monoclonal Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSRC
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SpecificityThis is a highly specific antibody against SRC.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityMonoclonal
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Clone number17AT28
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SourceThis Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC.
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Gene ID number6714
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Swiss ProtP12931
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Tested ApplicationsWB, IF
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Recommended dilutionsWB(1:500-2000)
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Cross reactivityHuman, Mouse
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThis gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
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Purification methodPurified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesASV; SRC1; THC6; c-SRC; p60-Src; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; SRC
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolSRC, NCOA1, NCOA3
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Short nameAnti-SRC
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TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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HostMouse (Mus musculus)
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IsotypeImmunoglobulin G (IgG)1
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Alternative nameSRC (17AT28) Monoclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), ASV and c-SRC and p60-Src and SRC1, SRC and IDBG-74081 and ENSG00000197122 and 6714, transferase activity, nuclei, Src and IDBG-211273 and ENSMUSG00000027646 and 20779, BT.61976 and IDBG-642561 and ENSBTAG00000008938 and 535742
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Gene info
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Identity
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Gene
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Long gene nameSRC proto-oncogene, non-receptor tyrosine kinase
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Synonyms gene
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Synonyms gene name
- v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
- Src family tyrosine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenuclear receptor coactivator 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
- Lysine acetyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear receptor coactivator 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
- Lysine acetyltransferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data