SGK3 Antibody

• Catalog number
  bs-6475R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SGK3 Primary Polyclonal Antibody
• Also known as
  SGK3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SGK3
• Specificity
  This is a highly specific antibody against SGK3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  40-90/496
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SGK3
• Gene ID number
  23678
• Swiss Prot
  Q96BR1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CISK; SGK2; SGKL; Serine/threonine-protein kinase Sgk3; Cytokine-independent survival kinase; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK3
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SGK3  
• Gene symbol
  C8orf44-SGK3, SGK3
• Short name
  Anti-SGK3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SGK3 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  serum/glucocorticoid regulated kinase family, member 3, SGK3 and IDBG-23987 and ENSG00000104205 and 100533105,23678, transferase activity, Cytoplasm

Gene info

• Identity
  HGNC:48354
• Gene
  C8orf44-SGK3
• Long gene name
  C8orf44-SGK3 readthrough
• Locus
  8q13.1
• Discovery year
  2013-05-10
• Entrez gene record
  100533105
• VEGA ID
  OTTHUMG00000183957

Gene info

• Identity
  HGNC:10812
• Gene
  SGK3
• Long gene name
  serum/glucocorticoid regulated kinase family member 3
• Synonyms gene
  • SGK2
  • SGKL
• Synonyms gene name
  • serum/glucocorticoid regulated kinase-like
  • serum/glucocorticoid regulated kinase family, member 3
• Locus
  8q13.1
• Discovery year
  1999-08-12
• Entrez gene record
  23678
• Pubmed identfication
  • 10585774
  • 10548550
• VEGA ID
  OTTHUMG00000164561

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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