PSME3 Antibody
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Catalog numberbs-4222R
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PricePlease ask
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Size0.1ml
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Long namePSME3 Primary Polyclonal Antibody
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Also known asPSME3 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPSME3
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SpecificityThis is a highly specific antibody against PSME3.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSME3
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Gene ID number10197
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenSubunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a donut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-TP53/p53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of TP53/p53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesPA28G; 11S regulator complex gamma subunit; 11S regulator complex subunit gamma; Activator of multicatalytic protease subunit 3; Ki antibody Ki antigen; Ki nuclear autoantigen; Ki, PA28 gamma; PA28 gamma; PA28gamma; Proteasome prosome, macropain activator subunit 3 PA28 gamma; Ki; Proteasome prosome, macropain activator subunit 3; Proteasome activator 28 gamma; Proteasome activator 28 subunit gamma; Proteasome activator complex subunit 3; Proteasome activator subunit 3; PSME3; PSME3_HUMAN;
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPSME3
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Short nameAnti-PSME3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePSME3 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetproteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki), HEL-S-283 and Ki and PA28-gamma and PA28G and PA28gamma and REG-GAMMA, PSME3 and IDBG-51809 and ENSG00000131467 and 10197, MDM2/MDM4 family protein binding, nuclei, Psme3 and IDBG-267041 and ENSMUSG00000078652 and 19192, PSME3 and IDBG-640458 and ENSBTAG00000019918 and 100336105
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Gene info
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Identity
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Gene
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Long gene nameproteasome activator subunit 3
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Synonyms gene name
- proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proteasome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data