Piccolo Antibody

• Catalog number
  bs-11354R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Piccolo Primary Polyclonal Antibody
• Also known as
  Piccolo PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Piccolo
• Specificity
  This is a highly specific antibody against Piccolo.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Piccolo
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a similar distribution and colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ACZ; Aczonin; Brain-derived HLMN protein; DKFZp779G1236; KIAA0559; Multidomain presynaptic cytomatrix protein; PCLO; PCLO_HUMAN; Piccolo presynaptic cytomatrix protein; Piccolo, mouse, homolog of antibody Pico; Presynaptic cytomatrix protein; Protein piccolo.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Piccolo  
• Gene symbol
  PCLO
• Short name
  Anti-Piccolo
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Piccolo Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13406
• Gene
  PCLO
• Long gene name
  piccolo presynaptic cytomatrix protein
• Synonyms gene name
  • piccolo (presynaptic cytomatrix protein)
• Synonyms
  • KIAA0559
  • DKFZp779G1236
  • ACZ
• Synonyms name
  • aczonin
• GenBank acession
  • AB011131
• Locus
  7q21.11
• Discovery year
  2001-06-25
• Entrez gene record
  27445
• Pubmed identfication
  • 8900486
  • 9628581
• RefSeq identity
  • NM_014510
• Classification
  • Zinc fingers
  • C2 domain containing
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000154853

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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