KDM5B Antibody

• Catalog number
  bs-6139R
• Price
  Please ask
• Size
  0.1ml

• Long name
  KDM5B Primary Polyclonal Antibody
• Also known as
  KDM5B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  KDM5B
• Specificity
  This is a highly specific antibody against KDM5B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  80-130/1544
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
• Gene ID number
  10765
• Swiss Prot
  Q9UGL1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CT31; PLU1; PUT1; PLU-1; JARID1B; PPP1R98; RBBP2H1A; Lysine-specific demethylase 5B; Cancer/testis antigen 31; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; Retinoblastoma-binding protein 2 homolog 1; RBP2-H1; KDM5B; RBBP2H1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KDM5B  
• Gene symbol
  KDM5B, PCAT6
• Short name
  Anti-KDM5B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  KDM5B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18039
• Gene
  KDM5B
• Long gene name
  lysine demethylase 5B
• Synonyms gene
  • JARID1B
• Synonyms gene name
  • Jumonji, AT rich interactive domain 1B (RBP2-like)
  • jumonji, AT rich interactive domain 1B
  • lysine (K)-specific demethylase 5B
• Synonyms
  • RBBP2H1A
  • PLU-1
  • CT31
  • PPP1R98
• Synonyms name
  • cancer/testis antigen 31
  • protein phosphatase 1, regulatory subunit 98
• GenBank acession
  • AJ243706
• Locus
  1q32.1
• Discovery year
  2004-01-28
• Entrez gene record
  10765
• Pubmed identfication
  • 11483573
  • 11478881
• RefSeq identity
  • NM_006618
• Classification
  • PHD finger proteins
  • Lysine demethylases
  • AT-rich interaction domain containing
• VEGA ID
  OTTHUMG00000041401

Gene info

• Identity
  HGNC:43714
• Gene
  PCAT6
• Long gene name
  prostate cancer associated transcript 6
• Synonyms gene
  • KDM5B-AS1
• Synonyms gene name
  • KDM5B antisense RNA 1 (head to head)
  • prostate cancer associated transcript 6 (non-protein coding)
• Synonyms
  • ncRNA-a2
  • PCAN-R1
  • KDM5BAS1
  • onco-lncRNA-96
• Synonyms name
  • prostate cancer-associated noncoding RNA 1
• GenBank acession
  • BI962506
  • AI806248
• Locus
  1q32.1
• Discovery year
  2012-02-02
• Entrez gene record
  100506696
• Pubmed identfication
  • 20887892
  • 23728290
• RefSeq identity
  • NR_046325
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000041399

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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