Jarid1C Antibody

• Catalog number
  bs-8178R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Jarid1C Primary Polyclonal Antibody
• Also known as
  Jarid1C PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Jarid1C
• Specificity
  This is a highly specific antibody against Jarid1C.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C
• Gene ID number
  11184
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.Tissue specificity:br>Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) . MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, seizures, facial dysmorphism.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  SmcX protein; Xe169 protein; DXS1272E; Histone demethylase JARID1C; JmjC domain containing protein SMCX; Jumonji AT rich interactive domain 1C; Jumonji/ARID domain-containing protein 1C; KDM5C; KDM5C_HUMAN; Lysine K specic demethylase 5C; Lysine-specic demethylase 5C; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; rbp2 like protein; Selected cDNA on X; Smcx homolog X chromosome; SmcX protein; Smcy homolog X linked; XE169; Xe169 protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Jarid1C  
• Gene symbol
  KDM5C
• Short name
  Anti-Jarid1C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Jarid1C Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11114
• Gene
  KDM5C
• Long gene name
  lysine demethylase 5C
• Synonyms gene
  • SMCX
  • JARID1C
  • MRX13
• Synonyms gene name
  • Jumonji, AT rich interactive domain 1C (RBP2-like)
  • Smcy homolog, X-linked (mouse)
  • jumonji, AT rich interactive domain 1C
  • mental retardation, X-linked 13
  • lysine (K)-specific demethylase 5C
• Synonyms
  • DXS1272E
  • XE169
• GenBank acession
  • Z29650
• Locus
  Xp11.22
• Discovery year
  1999-04-23
• Entrez gene record
  8242
• Pubmed identfication
  • 7951230
  • 8162017
  • 19826449
• RefSeq identity
  • NM_004187
• Classification
  • MicroRNA protein coding host genes
  • PHD finger proteins
  • Lysine demethylases
  • AT-rich interaction domain containing
• VEGA ID
  OTTHUMG00000021606
• Locus Specific Databases
  • KDM5C database at LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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