Anti-KDM5C / Jarid1C / SMCX Antibody

• Catalog number
  A1308-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  KDM5C
• Target Alternative Name
  MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E, Lysine-specific demethylase 5C, Jumonji/ARID domain-containing protein 1C
• Antibody Type
  Monoclonal
• Clone
  2E4-E1-G8
• Species Reactivities
  Human
• Immunogen Sequence
  Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
• Accession
  P41229
• Gene Id
  8242
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
• Purification
  Affinity purified
• Application
  WB, IF
• Positive Control
  WB: HeLa, 293, T$7D, MCF7 cell lysates; IF: HeLa cells
• Application And Usages
  WB; 1:1000; IF; 1:150
• Description
  Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KDM5C   Jarid1C   SMCX  
• Gene symbol
  KDM5C, KDM5C-IT1
• Short name
  Anti-KDM5C / Jarid1C / SMCX Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG2a
• Alternative name
  Antibody toKDM5C / Jarid1C / SMCX (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11114
• Gene
  KDM5C
• Long gene name
  lysine demethylase 5C
• Synonyms gene
  • SMCX
  • JARID1C
  • MRX13
• Synonyms gene name
  • Jumonji, AT rich interactive domain 1C (RBP2-like)
  • Smcy homolog, X-linked (mouse)
  • jumonji, AT rich interactive domain 1C
  • mental retardation, X-linked 13
  • lysine (K)-specific demethylase 5C
• Synonyms
  • DXS1272E
  • XE169
• GenBank acession
  • Z29650
• Locus
  Xp11.22
• Discovery year
  1999-04-23
• Entrez gene record
  8242
• Pubmed identfication
  • 7951230
  • 8162017
  • 19826449
• RefSeq identity
  • NM_004187
• Classification
  • MicroRNA protein coding host genes
  • PHD finger proteins
  • Lysine demethylases
  • AT-rich interaction domain containing
• VEGA ID
  OTTHUMG00000021606
• Locus Specific Databases
  • KDM5C database at LOVD

Gene info

• Identity
  HGNC:41384
• Gene
  KDM5C-IT1
• Long gene name
  KDM5C intronic transcript 1
• Synonyms gene name
  • KDM5C intronic transcript 1 (non-protein coding)
• Locus
  Xp11.22
• Discovery year
  2011-05-23
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000021604

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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