ITPR3 Antibody
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Catalog numberbs-6471R
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PricePlease ask
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Size0.1ml
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Long nameITPR3 Primary Polyclonal Antibody
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Also known asITPR3 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenITPR3
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SpecificityThis is a highly specific antibody against ITPR3.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ITPR3
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Gene ID number3710
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Tested ApplicationsIHC-P, IF(IHC-P)
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Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenInositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesIP3R-III; IP3 receptor isoform 3; 4 antibody 5-trisphosphate receptor; 5-trisphosphate receptor type 3; FLJ36205; Inositol 1; Inositol 1,4,5 trisphosphate receptor type 3; IP3 receptor; IP3R 3; IP3R; IP3R3; ITPR 3; ITPR3; ITPR3_HUMAN; Type 3 inositol 1; Type 3 inositol 1,4,5 trisphosphate receptor; Type 3 InsP3 receptor.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolITPR3
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Short nameAnti-ITPR3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameITPR3 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetinositol 1,4,5-trisphosphate receptor, type 3, IP3R and IP3R3, ITPR3 and IDBG-82972 and ENSG00000096433 and 3710, inositol 1, nuclei, Itpr3 and IDBG-156294 and ENSMUSG00000042644 and 16440, ITPR3 and IDBG-629118 and ENSBTAG00000013245 and 281879
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Gene info
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Identity
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Gene
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Long gene nameinositol 1,4,5-trisphosphate receptor type 3
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Synonyms gene name
- inositol 1,4,5-triphosphate receptor, type 3
- inositol 1,4,5-trisphosphate receptor, type 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-06-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Inositol 1,4,5-triphosphate receptors
- Protein phosphatase 1 regulatory subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data