Fast skeletal Myosin Antibody

• Catalog number
  bs-5159R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Fast skeletal Myosin Primary Polyclonal Antibody
• Also known as
  Fast skeletal Myosin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Fast skeletal Myosin
• Specificity
  This is a highly specific antibody against Fast skeletal Myosin. This antibody may recognize myosin light chain 5, myosin light chain 7, or myosin regulatory light chain 10
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/170
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRLC2
• Gene ID number
  29895
• Swiss Prot
  Q96A32
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins . Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MRLC2; MYL11; HUMMLC2B; Myosin regulatory light chain 2, skeletal muscle isoform; Fast skeletal myosin light chain 2; MLC2B; MYLPF
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Fast   skeletal   Myosin  
• Gene symbol
  MYL1, MYBPC2, MYLPF
• Short name
  Anti-Fast skeletal Myosin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Fast skeletal Myosin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7582
• Gene
  MYL1
• Long gene name
  myosin light chain 1
• Synonyms gene name
  • myosin, light polypeptide 1, alkali; skeletal, fast
  • myosin, light chain 1, alkali; skeletal, fast
• Locus
  2q34
• Discovery year
  1986-01-01
• Entrez gene record
  4632
• Pubmed identfication
  • 2304459
  • 3422212
• RefSeq identity
  • NM_079420
• Classification
  • Myosin light chains, class 1
• VEGA ID
  OTTHUMG00000132992

Gene info

• Identity
  HGNC:7550
• Gene
  MYBPC2
• Long gene name
  myosin binding protein C2
• Synonyms gene name
  • myosin-binding protein C, fast-type
• Synonyms
  • MYBPCF
  • MGC163408
  • fsMyBP-C
• Synonyms name
  • fast-type muscle myosin-binding-protein C
  • fast skeletal-type muscle myosin-binding-protein C
• Locus
  19q13.33
• Discovery year
  1993-12-15
• Entrez gene record
  4606
• Pubmed identfication
  • 8375400
• RefSeq identity
  • NM_004533
• Classification
  • I-set domain containing
  • Myosin binding proteins
• VEGA ID
  OTTHUMG00000183040

Gene info

• Identity
  HGNC:29824
• Gene
  MYLPF
• Long gene name
  myosin light chain, phosphorylatable, fast skeletal muscle
• Synonyms
  • MRLC2
  • HUMMLC2B
  • MYL11
• Synonyms name
  • myosin, light chain 11, regulatory
  • myosin regulatory light chain 2
• GenBank acession
  • AF363061
• Locus
  16p11.2
• Discovery year
  2009-03-06
• Entrez gene record
  29895
• Pubmed identfication
  • 6179945
• RefSeq identity
  • NM_013292
• Classification
  • Myosin light chains, class 2
• VEGA ID
  OTTHUMG00000132399

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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