FAM3C Antibody

• Catalog number
  bs-7862R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FAM3C Primary Polyclonal Antibody
• Also known as
  FAM3C PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FAM3C
• Specificity
  This is a highly specific antibody against FAM3C.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FAM3C
• Gene ID number
  10447
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Fam3c; FAM3C_HUMAN; family with sequence similarity 3, member C; GS3786;ILEI; Interleukin-like EMT inducer; Predicted osteoblast protein; Protein FAM3C.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FAM3C  
• Gene symbol
  FAM3C
• Short name
  Anti-FAM3C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FAM3C Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  family with sequence similarity 3, member C, ILEI, FAM3C and IDBG-38333 and ENSG00000196937 and 10447, cytokine activity, Extracellular, Fam3c and IDBG-129573 and ENSMUSG00000029672 and 27999, FAM3C and IDBG-634725 and ENSBTAG00000007976 and 615690

Gene info

• Identity
  HGNC:18664
• Gene
  FAM3C
• Long gene name
  FAM3 metabolism regulating signaling molecule C
• Synonyms gene name
  • family with sequence similarity 3 member C
• Synonyms
  • GS3876
  • ILEI
• Synonyms name
  • predicted osteoblast protein
  • interleukin-like EMT inducer
  • interleukin-like epithelial-mesenchymal transition inducer
• GenBank acession
  • D87120
• Locus
  7q31.31
• Discovery year
  2002-06-18
• Entrez gene record
  10447
• Pubmed identfication
  • 12160727
• RefSeq identity
  • NM_001040020
• VEGA ID
  OTTHUMG00000156979

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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