EYA1 Antibody

• Catalog number
  bs-20158R
• Price
  Please ask
• Size
  0.1ml

• Long name
  EYA1 Primary Polyclonal Antibody
• Also known as
  EYA1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  EYA1
• Specificity
  This is a highly specific antibody against EYA1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  260-310/592
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EYA1
• Gene ID number
  2138
• Swiss Prot
  Q99502
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears. Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BOP; BOR; BOS1; OFC1; Eyes absent homolog 1; EYA1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EYA1  
• Gene symbol
  EYA1
• Short name
  Anti-EYA1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  EYA1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  eyes absent homolog 1 (Drosophila), BOP and BOR and BOS1 and OFC1, EYA1 and IDBG-25014 and ENSG00000104313 and 2138, metal ion binding, nuclei, Eya1 and IDBG-134456 and ENSMUSG00000025932 and 14048, EYA1 and IDBG-644711 and ENSBTAG00000011298 and 511188

Gene info

• Identity
  HGNC:3519
• Gene
  EYA1
• Long gene name
  EYA transcriptional coactivator and phosphatase 1
• Synonyms gene
  • BOR
• Synonyms gene name
  • eyes absent (Drosophila) homolog 1
  • eyes absent homolog 1 (Drosophila)
• GenBank acession
  • AJ000098
• Locus
  8q13.3
• Discovery year
  1996-12-12
• Entrez gene record
  2138
• Pubmed identfication
  • 9020840
• RefSeq identity
  • NM_000503
  • NM_172060
• Classification
  • EYA transcriptional coactivator and phosphatases
• VEGA ID
  OTTHUMG00000149894

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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