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Rabbit Anti Human EYA1 Antibody-Biotin

  • Catalog number
    CSB-PA857862LD01HU_50ug
  • Product name
    Rabbit Anti Human EYA1 Antibody-Biotin
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human EYA1, Biotin
  • Short name
    Anti-EYA1
  • Synonym name
    EYA1 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Biotin
  • Antibody isotype
    IgG
  • UniProt ID
    Q99502
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Human Eyes absent homolog 1 protein (168-321AA)
  • Immunogen species
    Human
  • Alias
    Eyes absent homolog 1, EYA1
  • Background
    Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19234442). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    EYA1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Eyes absent homolog 1
  • Alternative to gene target
    • [ "eyes absent homolog 1 (Drosophila)", "BOP and BOR and BOS1 and OFC1", "EYA1 and IDBG-25014 and ENSG00000104313 and 2138", "metal ion binding", "nuclei", "Eya1 and IDBG-134456 and ENSMUSG00000025932 and 14048", "EYA1 and IDBG-644711 and ENSBTAG00000011298 and 511188" ]
  • Gene target
    EYA1 -
    • Gene info
  • Gene symbol
    EYA1
  • Label
    Biotin
  • label filter
    • Biotin
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, rabbit-anti