ERCC6 Antibody
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Catalog numberbs-14082R
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PricePlease ask
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Size0.1ml
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Long nameERCC6 Primary Polyclonal Antibody
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Also known asERCC6 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenERCC6
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SpecificityThis is a highly specific antibody against ERCC6.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range240-275/1493
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Subcellular locationNucleus
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ERCC6
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Gene ID number2074
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Swiss ProtQ03468
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Tested ApplicationsIHC-P, IF(IHC-P)
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Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenEssential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCSB; CKN2; COFS; ARMD5; COFS1; RAD26; UVSS1; DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB; ERCC6
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolERCC6
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Short nameAnti-ERCC6
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameERCC6 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetexcision repair cross-complementing rodent repair deficiency, complementation group 6, ARMD5 and CKN2 and COFS and COFS1 and CSB and RAD26 and UVSS1, ERCC6 and IDBG-304121 and ENSG00000225830 and 2074, protein N-terminus binding, nuclei, Ercc6 and IDBG-147857 and ENSMUSG00000054051 and 319955, ERCC6 and IDBG-631777 and ENSBTAG00000032527 and 522908
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Gene info
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Identity
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Gene
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Long gene nameERCC excision repair 6, chromatin remodeling factor
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Synonyms gene
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Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 6
- excision repair cross-complementation group 6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ERCC excision repair associated
- B-WICH chromatin-remodelling complex subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data