Cullin 5 Antibody

• Catalog number
  bs-10059R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Cullin 5 Primary Polyclonal Antibody
• Also known as
  Cullin 5 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Cullin 5
• Specificity
  This is a highly specific antibody against Cullin 5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cullin 5
• Gene ID number
  1729
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CUL 5; CUL-5; CUL5; CUL5_HUMAN; Cullin-5; Cullin5; VACM 1; VACM-1; VACM1; Vasopressin activated calcium mobilizing receptor 1; Vasopressin activated calcium mobilizing receptor; Vasopressin-activated calcium-mobilizing receptor 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cullin  
• Gene symbol
  CUL5, DCUN1D5
• Short name
  Anti-Cullin 5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Cullin 5 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2556
• Gene
  CUL5
• Long gene name
  cullin 5
• Synonyms
  • VACM-1
• GenBank acession
  • X81882
• Locus
  11q22.3
• Discovery year
  1998-12-23
• Entrez gene record
  8065
• Pubmed identfication
  • 8681378
  • 9037604
• Classification
  • Cullins
• VEGA ID
  OTTHUMG00000166369

Gene info

• Identity
  HGNC:28409
• Gene
  DCUN1D5
• Long gene name
  defective in cullin neddylation 1 domain containing 5
• Synonyms gene name
  • DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
• Synonyms
  • MGC2714
  • FLJ32431
• Locus
  11q22.3
• Discovery year
  2005-10-04
• Entrez gene record
  84259
• Pubmed identfication
  • 15988528
• RefSeq identity
  • NM_032299
• VEGA ID
  OTTHUMG00000165822

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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