Ceramide synthase 2 Antibody
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Catalog number
bs-5077R
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Price
Please ask
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Size
0.1ml
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Long name
Ceramide synthase 2 Primary Polyclonal Antibody
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Also known as
Ceramide synthase 2 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Ceramide synthase 2
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Specificity
This is a highly specific antibody against Ceramide synthase 2.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
230-261/380
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Subcellular location
Lumenal
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ceramide synthase 2
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Gene ID number
29956
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Swiss Prot
Q96G23
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
L3; LASS2; SP260; TMSG1; Ceramide synthase 2; CerS2; LAG1 longevity assurance homolog 2; Tumor metastasis-suppressor gene 1 protein
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
CERS2
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Short name
Anti-Ceramide synthase 2
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Ceramide synthase 2 Polyclonal Antibody
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
ceramide synthase 2
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Synonyms gene
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Synonyms gene name
- longevity assurance (LAG1, S. cerevisiae) homolog 2
- LAG1 longevity assurance homolog 2 (S. cerevisiae)
- LAG1 homolog, ceramide synthase 2
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-09-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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